Heisman Trophy and National Championship Odds: Top Bets and Analysis for the 2025 NCAAF Season
Dive into the latest Heisman Trophy and National Championship odds for the 2025 NCAAF season, featuring top bets, player analysis, and key insights.

Heisman Trophy Favorites
Arch Manning, QB, Texas (+650)
Arch Manning is the frontrunner for the Heisman Trophy, stepping into a Texas program brimming with talent. With a strong offensive line and a national stage, Manning has all the tools to shine. However, his lack of a full-season track record and the pressure of preseason hype could be hurdles. Historically, only one preseason favorite has won the Heisman in the past 16 years.
Cade Klubnik, QB, Clemson (+900)
In his third year as a starter, Klubnik has a deep receiving corps and a favorable schedule. While he’s been efficient, his ceiling remains a question. The Heisman often rewards flashy, video-game stats, and Klubnik’s steady play might not be enough to secure the trophy.
Garrett Nussmeier, QB, LSU (+900)
Nussmeier has the arm talent and confidence to put up Heisman numbers, but his turnover-prone nature and LSU’s uncertain receiving corps are concerns. If he can string together consistent performances, he could push LSU into the national spotlight.
National Championship Favorites
Ohio State (+550)
Coming off a national championship, Ohio State has momentum and a winning culture. However, the loss of key players and coordinators, along with a new quarterback, raises questions about their depth and experience.
Texas (+550)
Texas, led by Arch Manning, is the preseason favorite to win the SEC and the national title. However, the Longhorns lost key staffers, and Georgia remains a formidable threat. Any misstep could derail their championship aspirations.
Penn State (+650)
Penn State has a strong roster with Drew Allar at quarterback and a formidable backfield duo. However, James Franklin’s record in big games and a new defensive system under Jim Knowles add uncertainty to their championship bid.
Another Bet to Consider
Kansas State to win Big 12 (+1000)
Kansas State’s odds dropped significantly after a Week 0 loss to Iowa State, but the game was heavily influenced by weather and sloppy conditions. With a favorable schedule and strong playmakers, the Wildcats are still in the race for the Big 12 title.